The best time to drink your homemade juice is before you eat. The juice can tide you over between meals. Also, your system is able to use the nutrients more efficiently if juice is drunk on an empty stomach. By drinking juice first, it's much less likely that you'll overeat at your next meal.
The best juicers can run at a slow speed, maximizing nutritional benefit. Faster juicers overheat, which leads to a breakdown in the quality of the juice, losing vital nutrients in the process.
If you are concerned with your intake of fat, consider adding negative-calorie foods to your juice blends.
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